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Provista Blog > 6 Types of Biomarkers in Cancer Detection

Provista Blog

6 Types of Biomarkers in Cancer Detection

Posted by Provista Diagnostics on October 14, 2016

There are several types of biomarkers, which fulfill different roles across the continuum of care. By analyzing biomarkers, diagnostic tests may be able to provide information about early tumor development to detect breast cancer at an early, more treatable stage. These biomarkers can be helpful in managing patients in the following settings: 

1. Risk Assessment 

These biomarkers are frequently associated with a predisposition to cancer and can inform a woman's future risk of developing breast cancer. Healthcare providers often recommend that individuals with these gene mutations consider more frequent screenings in an attempt to detect breast cancer at an early stage. 

2. Screening/Detection

Biomarkers for screening and detection are real-time indicators of the presence of cancer. The body may respond to the presence of a tumor by creating and releasing immune factors (such as antibodies) or by shedding serum proteins, circulating tumor cells and DNA fragments into the bloodstream.
Download: Why Protein Biomarkers Are The Key To Improving Cancer Detection

3. Diagnosis

While the only way to confirm a breast cancer diagnosis is by biopsy, biomarkers can aid in diagnosis and help determine the primary origin of the tumor.

4. Prognosis

Prognostic biomarkers may provide information about a patient's expected outcome, regardless of therapy. 
Some breast cancers are more aggressive than others and biomarkers can help determine which cancers may grow rapidly and/or metastasize. 

5. Prediction

Biomarkers may be used to predict a patient's response to treatment or to determine the optimal drug dose or type used for breast cancer treatment. Since breast cancer is a heterogeneous disease, different cancers can respond differently to the same treatment methods. 

6. Monitoring:

Biomarkers may be used to predict and monitor a patient's breast cancer recurrence of the disease after treatment. 



Videssa® Breast is a diagnostic test for breast cancer detection and is not recommended for screening. Oncotype Dx is a registered trademark of Genomic Health, Inc. and Mammaprint is a registered trademark of Agendia, Inc. 

By using different types of biomarkers in cancer detection that are specifically geared towards breast cancer, another biological view of current disease state is available in addition to the anatomical view of breast imaging. Types of cancer biomarkers are capable of detecting, predicting and diagnosing disease. These biomarkers can also assist in personalized prognosis and treatment strategies as well as recurring monitoring for the disease. 

To learn more about the role different types of biomarkers play in cancer detection, read our guide below: 

Provista Diagnostics

Provista Diagnostics

At Provista Diagnostics, our mission is to develop world-class diagnostic tests for indications in breast and gynecologic cancers. As a leading diagnostics company, our aim is to create, produce and market innovative solutions for unmet clinical needs. Our products and services help to diagnose diseases and inform better clinical decisions, thus enhancing women’s health and quality of life. We do this in a responsible and ethical manner with a commitment to excellence in every aspect of our business.